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JULÄINE™ collagen-stimulating injectable treatment at Aesthetics Lab London

JULÄINE™ Treatment in London

JULÄINE™ (Julaine) is an injectable skin bio-activator designed to stimulate your skin’s own collagen production, for the correction of mild to severe nasolabial folds.

At Aesthetics Lab, JULÄINE™ offers a regenerative approach to facial rejuvenation for patients looking for subtle, progressive results. Rather than simply adding volume, it works with the skin’s natural processes, using unique LASYNPRO™ technology with Lactic Acid-based microspheres to stimulate collagen production over time.

  • Stimulates natural collagen production
  • Treats mild to severe nasolabial folds
  • Supports gradual, natural-looking rejuvenation

No. of sessions
Personalised treatment plan, with up to 3 treatment sessions where appropriate


Treatment time
30 minutes


Recovery time
Most patients can return to normal daily activities immediately


What Is JULÄINE™?

JULÄINE™ is a regenerative injectable designed to stimulate your skin’s own collagen production. Collagen is one of the proteins responsible for keeping skin firm, supported and resilient, but its production naturally changes with age. As this happens, the skin can lose some of its structure and lines and folds may become more noticeable.

Rather than simply adding volume to create an immediate filling effect, JULÄINE™ works by encouraging the skin to produce new collagen. It uses patented LASYNPRO™ technology, made up of highly uniform Lactic Acid-based microspheres that are injected into the deeper layers of the skin.

Once in the tissue, these microspheres stimulate fibroblasts, the cells involved in producing collagen. The microspheres are biocompatible and biodegradable, meaning they are gradually broken down and absorbed by the body as the collagen renewal process takes place.

Because JULÄINE™ works by stimulating this natural process, results develop progressively over the weeks following treatment. The aim is a gradual improvement in the firmness, structure and overall quality of the treated skin, rather than an immediate or overly noticeable change.

What Can We Treat With JULÄINE™?

JULÄINE™ has been clinically studied for the correction of mild to severe nasolabial folds, the lines or folds that extend from the sides of the nose towards the corners of the mouth.

Your Doctor will advise whether JULÄINE™ is suitable for your concerns during your consultation.

Book your consultation

Treatment Step-by-Step

Step 1: Consultation

Your treatment starts with a consultation at Aesthetics Lab.

We will assess your skin, discuss the changes you have noticed and find out what you would like to achieve from treatment. Your medical history will also be reviewed to make sure JULÄINE™ is appropriate for you.

This is also an opportunity to discuss how collagen-stimulating treatments differ from more traditional injectable treatments. JULÄINE™ works progressively, so it is important that you understand how your results are expected to develop and what can realistically be achieved.

If JULÄINE™ is suitable, we will create a personalised treatment plan and explain the number of sessions that may be recommended.

Your medical consultation costs £150. This fee is redeemable against any medical treatment and is non-refundable.

Step 2: During Your Treatment

Before treatment, the areas to be treated will be carefully assessed and marked.

JULÄINE™ is then introduced into the deeper layers of the skin. The product can be administered using appropriate injection techniques selected by your medical practitioner according to the treatment area and your individual needs.

Its smooth LASYNPRO™ microspheres are designed to integrate into the tissue and begin the process of stimulating new collagen production.

As with all injectable treatments at Aesthetics Lab, careful assessment and precise treatment are central to achieving a natural-looking result.

Step 3: After Your Treatment

You may notice some temporary redness, swelling, tenderness or bruising around the injection sites following treatment. These effects would usually be expected to settle within a few days.

Most patients can return to their usual daily activities immediately after their appointment.

You will be given appropriate aftercare instructions, which may include massaging the treated area as directed by your practitioner. You should follow these instructions carefully.

Unlike a treatment designed to produce an immediate filling effect, JULÄINE™ continues to work after you leave the clinic. Over the following weeks, collagen renewal gradually develops, helping to smooth the treated folds and improve the firmness and quality of the skin.

Further treatment sessions may be recommended 2–6 weeks apart. The interval and number of sessions will be determined following assessment by your treating clinician.

Frequently Asked Questions

Is JULÄINE™ a dermal filler?

JULÄINE™ is an injectable treatment, but its approach is different from simply using a traditional filler to add immediate volume.

It is described as a skin bio-activator, meaning that its primary role is to activate the skin’s own collagen production. The improvement therefore develops progressively as new collagen forms.

For patients who prefer subtle changes and want to support their own collagen production, this regenerative approach may be particularly appealing.

What is LASYNPRO™ technology?

LASYNPRO™ is the proprietary technology behind JULÄINE™.

It uses highly uniform Lactic Acid-based microspheres designed to integrate smoothly within the tissue. These microspheres stimulate fibroblast cells and encourage the production of new collagen before being naturally absorbed by the body.

The aim is to create gradual improvements in the skin’s underlying collagen structure rather than an artificial or overly dramatic change.

What areas can JULÄINE™ treat?

JULÄINE™ has been clinically studied for the correction of mild to severe nasolabial folds, which run from the sides of the nose towards the corners of the mouth.

Your Doctor will advise whether JULÄINE™ is suitable for your concerns during your consultation.

When will I see results from JULÄINE™?

JULÄINE™ is designed to work gradually.

As the treatment stimulates your body’s own collagen production, improvements develop over the weeks following your appointment rather than appearing as an immediate final result.

This progressive process can help create a subtle result that feels in keeping with your existing features.

How long do JULÄINE™ results last?

Results develop gradually over the weeks and months following treatment.

How many JULÄINE™ treatments will I need?

Your treatment plan will depend on your starting point and the degree of correction required.

Further treatment sessions may be recommended 2–6 weeks apart. The interval and number of sessions will be determined following assessment by your treating clinician.

Your practitioner will advise you on the most appropriate schedule rather than treating to a predetermined number of sessions.

How much does JULÄINE™ cost?

JULÄINE™ treatment at Aesthetics Lab starts from £1,000 per session.

As your treatment plan may include up to three sessions, the total cost will depend on the degree of correction you need. Your practitioner will confirm your personalised plan and its cost at your consultation, before any treatment goes ahead.

Is there any downtime after JULÄINE™?

Most patients can return to their normal daily activities immediately after treatment.

As JULÄINE™ is an injectable treatment, temporary reactions such as redness, swelling, bruising or tenderness can occur around the treatment area. These commonly settle within a few days.

You will receive full aftercare advice following your appointment.

Does JULÄINE™ give an immediate result?

JULÄINE™ is designed for progressive collagen regeneration rather than an immediate final result.

The treatment activates the biological processes involved in collagen production, so improvements continue to develop over the weeks following treatment. This gradual response is an important part of the JULÄINE™ approach and helps create natural-looking rejuvenation.

Who is suitable for JULÄINE™?

JULÄINE™ is intended for immune-competent adults. It may be suitable if you are looking for a gradual, natural-looking improvement in nasolabial folds.

As with any injectable treatment, it will not be appropriate for everyone. Your medical history, skin and treatment goals will therefore be carefully assessed during your consultation before treatment is recommended.

Who performs JULÄINE™ treatment at Aesthetics Lab?

JULÄINE™ is administered by Dr Rezhaw Luca Karadaghi, a surgeon and aesthetics clinician educated at King’s College London and the University of Oxford, and Dr Tajel Patel, an award-winning dental and aesthetic practitioner and facial aesthetics trainer.

Treatment is available at both our Belgravia and Primrose Hill clinics in London.

Discover JULÄINE™ at Aesthetics Lab

If you have noticed deeper nasolabial folds, JULÄINE™ offers a regenerative approach centred around stimulating your own collagen production.

At Aesthetics Lab, we will assess your skin and facial structure carefully before recommending treatment, ensuring that JULÄINE™ is appropriate for both your concerns and the result you would like to achieve.

JULÄINE™ treatments at Aesthetics Lab are carried out by Dr Rezhaw Luca Karadaghi, a surgeon and aesthetics clinician educated at King’s College London and the University of Oxford, and Dr Tajel Patel, an award-winning dental and aesthetic practitioner and facial aesthetics trainer. JULÄINE™ is available at both our Belgravia and Primrose Hill clinics.

Exploring other collagen-stimulating options? Compare JULÄINE™ with Sculptra and Profhilo, or see other ways we treat nasolabial folds.

Book your JULÄINE™ consultation at Aesthetics Lab in Belgravia or Primrose Hill.

Book your consultation

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Danyal Abbasi
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I had e great experience with my hydrafacial and laser treatment at Aesthetics lab. Dr iffat khattak was knowledgeable and great lady . Im thrilled with the results and highly recommend
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Liz Riazanski
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I recently had a facial at Aesthetics Lab, and I can say that without a doubt it was the best treatment I have ever received. From the consultation which was very thorough, in which we discussed each of my concerns in depth, to the facial itself, which was incredible. I have had many facials in the past and none of them have been of this high standard. I was then recommended some products which I purchased from the clinic and have been using ever since. They have done wonders for my skin, and I will definitely be returning! I cannot recommend Aesthetics Lab enough, the staff are so lovely and accommodating and the treatments are fantastic!
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Amanda Beety
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Emma and the aesthetics lab team are INCREDIBLE! I very rarely write reviews, but I am so happy with my experience with Emma, that I have to! I have recently been trying to explore how to optimise my skin. This is all new to me, so I was a bit hesitant and unsure going into the process. Unfortunately, I had a very bad experience at a different clinic with a facial-gone-wrong, and am dealing with ongoing acne as a result. I had nearly lost hope that skincare could be for me, but then I found Aesthetics lab! Carolyn helped me with my initial consultation. She was very welcoming and empathetic to my situation, making me feel very comfortable. I had my first session the same day with Emma. I did a light treatment and the experience was fantastic. Emma immediately made me feel comfortable. She understood the concerns and hesitations that I had and was very patient answering my many questions. I felt very calm and could tell how experienced she was. I had such a great experience that I booked again and came back for my second treatment with Emma that same week. This time I got a hydra facial. It was again, a fantastic experience. I was so impressed with all of her knowledge on how the products work, her advice on what my skin might respond best to, and her understanding and empathy towards my situation. I really trust her and the advice that she gave towards my skincare routine. I have already seen improvements and am telling my friends to book their appointments with Emma! She is truly the best!
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IC
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Staff are friendly, knowledgeable and experienced. You can ask them for advice on different treatments. I didn’t know what to expect but I’m pleased with the results.
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sasha rodham
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I have recently finished a course of Laser Hair Removal with Aesthetics Lab and could not recommend it enough , from the moment I walked in the staff were so welcoming and professional. The clinic itself is accessible, modern and exceptionally clean. I had 6 sessions targeting under my arms and legs which was painless and really effective with no redness or rashes which I have previously experienced when waxing, my only regret is I didn't visit sooner!!
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Nava Sokolovsky
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The staff are very welcoming and professional, and have made me feel at ease and relaxed during treatments. The clinic itself is lovely and clean, and clearly looks like it's kept up to a high standard. Ive had two treatments here so far, eyebrow semi permanent tattoo with Charli and laser hair removal with Charlotte and both therapists have been knowledgeable, experienced, and friendly, and I've been very pleased with the results of the treatments.
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